Skip to content
oprimaze.

The position

GLP-1 changed weight loss. Oprimaze solves what GLP-1 leaves behind.

The industry gave people a way to lose weight. But most regain it within a year of stopping. Oprimaze was built around the gap everyone else ignored.

The problem

GLP-1 was a breakthrough. The exit from it wasn't.

GLP-1 therapies have transformed weight management — proven, widely prescribed, effective. But the industry built the treatment and ignored the transition. When the therapy ends, the appetite suppression and metabolic recalibration withdraw. The body's adaptive responses — calibrated to restore lost weight — reactivate.

80%.

Regain within 5 years

Without structured maintenance

.

Regain within 12 months

After stopping GLP-1

0.

Standard exit protocols

After GLP-1 therapy

Known GLP-1 limitations

Why GLP-1 alone isn't the full answer.

Nausea & GI side effects

In the STEP 1 trial, roughly 44% of participants reported nausea — a leading reason for early discontinuation (Wilding et al., NEJM 2021).

Injection barrier

Weekly injections aren't a fit for everyone, and adherence drops over time.

Cost & access

Often hundreds of dollars a month, even with insurance — ongoing therapy stays out of reach for many.

No exit pathway

When therapy ends, there's no structured plan for the predictable rebound.

Who it's for

Built for the exit — at any age.

Whether you're stepping off a GLP-1 or protecting a result you earned the hard way, the system asks for no injections, no prescriptions, and no clinic visits — just a spray that travels as easily as you do.

Man holding the Oprimaze Weight Loss nasal spray at home

What's missing

  • One product for two distinct phases
  • Slow, low-bioavailability oral delivery
  • Needles, GI side effects, or stimulants
  • No support after the weight comes off

What Oprimaze delivers

  • Two sprays for two distinct phases
  • Fast nasal delivery, minutes not hours
  • Hemp-derived actives (THCV · CBD · CBC), clean labels
  • A maintenance ritual designed to keep results