The position
GLP-1 changed weight loss. Oprimaze solves what GLP-1 leaves behind.
The industry gave people a way to lose weight. But most regain it within a year of stopping. Oprimaze was built around the gap everyone else ignored.
The problem
GLP-1 was a breakthrough. The exit from it wasn't.
GLP-1 therapies have transformed weight management — proven, widely prescribed, effective. But the industry built the treatment and ignored the transition. When the therapy ends, the appetite suppression and metabolic recalibration withdraw. The body's adaptive responses — calibrated to restore lost weight — reactivate.
80%.
Regain within 5 years
— Without structured maintenance
⅔.
Regain within 12 months
— After stopping GLP-1
0.
Standard exit protocols
— After GLP-1 therapy
Known GLP-1 limitations
Why GLP-1 alone isn't the full answer.
Nausea & GI side effects
In the STEP 1 trial, roughly 44% of participants reported nausea — a leading reason for early discontinuation (Wilding et al., NEJM 2021).
Injection barrier
Weekly injections aren't a fit for everyone, and adherence drops over time.
Cost & access
Often hundreds of dollars a month, even with insurance — ongoing therapy stays out of reach for many.
No exit pathway
When therapy ends, there's no structured plan for the predictable rebound.
Who it's for
Built for the exit — at any age.
Whether you're stepping off a GLP-1 or protecting a result you earned the hard way, the system asks for no injections, no prescriptions, and no clinic visits — just a spray that travels as easily as you do.

What's missing
- One product for two distinct phases
- Slow, low-bioavailability oral delivery
- Needles, GI side effects, or stimulants
- No support after the weight comes off
What Oprimaze delivers
- Two sprays for two distinct phases
- Fast nasal delivery, minutes not hours
- Hemp-derived actives (THCV · CBD · CBC), clean labels
- A maintenance ritual designed to keep results